Biography:
Cannataro has her expertise in evaluation and passion in improving the health and wellbeing particularly on field of nutrition and nutritional supplementation. He’s involved in several project regarding diet and supplement evaluation. Recently He’s working on the very brand new field of miRNA, purposing it as novel biomarkers, in antioxidant and immune status. Other interesting filed is ketogenic diet, applied not only as usefull tool to loose weight but to menage deseases such migraine, lipoedema and epilepsy.
Abstract:
ROS (Reactive Oxigen Species) are instable molecules syntetized either in physiological and patological situation, we are exposed to then because of UV ray, pollution, combustions, stress, but they are naturally producted during cellular respiration too. Our body posses a machinery to inactivate it (vitamins and antioxidant enzymes). If there’s an imbalance beetwen ROS production and inactivation by our body, they could modify organic molecules, particularly phospholipids (modifying structures and permeability of membranes), proteins (cutting down their biological function) and finally DNA (becoming a potential carcinogen) altering normal activity of cells. So it is mandatory, for a good health state, to menage this delicate equilibrium. We demonstrated how diet (in particulare ketogenic diet) could positively regulate this mechanism and we assessed it via miRNA, small circulating RNA sequences, a novel way to have biological marker, we used too it to check diet progression and immunological status.